Colchicine
Drug Class: Uric acid drugs (Anti-inflammatory)
Brand Names: Colcrys, Golperba, Mitigare
Dosages
For prevention: 0.6 to 1.2 mg daily in one or two doses. (Maximum dose is 1.2 mg/day.)
To stop acute attacks (Colcrys only): 1.2 mg at the first sign of a flare followed by 0.6 mg an hour later.
Potential Side Effects
Diarrhea; nausea; nerve pain; vomiting; stomach pain.
Special Instructions
You should not take grapefruit and grapefruit juice while taking this drug, because doing so affects the levels of the drug in your body.
Drink plenty of fluids while taking this medication.
Stop taking this medication and call your doctor if you have diarrhea, nausea, stomach pain or vomiting.
Take with food or an antacid.
Be Aware
Before taking colchicine, tell your doctor if you take NSAIDs, cancer medications, heparin, nitrofurantoin or zidovudine. Special caution is required in people who have an ongoing infection or who are using immunosuppressive drugs. Death due to colchicine toxicity have been reported in patients taking this medication with certain antibiotics and antifungals, particularly clarithromycin (Biaxin). Make sure your doctor knows about your entire health history.
LAST UPDATED: 03/07/2019
