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Acetaminophen with codeine

 Drug Class: Analgesics (Opioid)
 Brand Names: Cocet, Cocet Plus, Tylenol with Codeine No.2, Tylenol with Codeine No.3, Tylenol with Codeine No.4

Dosages

In a combination pill, 15 to 60 mg codeine and 150 to 600 mg acetaminophen every 4 hours as needed.

Dosages for children: The dosages listed above are those typically prescribed for adults aged 18-65. Dosages for children can vary. Ask your doctor about the appropriate dosage for your child.

Potential Side Effects

Constipation; dizziness; drowsiness; itching; lightheadedness; mental confusion; nausea; sedation; shortness of breath; urinary retention; vomiting.

Special Instructions

Do not drive or perform other potentially dangerous activities until you know whether the medication will impair your ability to do them safely.

Do not increase the dose on your own or stop treatment abruptly unless advised by a doctor.

Be Aware

This medicine contains acetaminophen. Do not use with any other products containing acetaminophen. Too much acetaminophen can cause serious liver damage or death. Limit the amount of acetaminophen you take to 3000 mg/day unless otherwise directed by your doctor. Drinking alcohol increases your risk of liver damage. Tell your doctor if you have a history of liver disease or alcohol or drug abuse, or if you have three or more alcoholic drinks daily. Also tell your doctor if you take the blood-thinning drug warfarin (Coumadin). Acetaminophen prolongs the time that drug is active in your body, increasing bleeding risk. Your doctor may need to adjust your dosage. Rarely, acetaminophen may cause serious skin reactions, including Stevens-Johnson syndrome, which can be deadly. Stop taking acetaminophen and call your doctor if you develop a skin rash.

Opioids can slow breathing and suppress the cough reflex. Before taking an opioid, tell your doctor if you have a history of lung disease or breathing difficulties. Taking opioids with certain other drugs can increase the risk of dangerous side effects. Especially tell your doctor if you take antihistamines (allergy medications), tranquilizers, sleeping pills, muscle relaxants or other pain medication, or if you have a history of alcohol or drug abuse.

LAST UPDATED: 03/27/2014

The Arthritis Today Drug Guide is meant for education – not self-medicating. Arthritis Today, the Arthritis Foundation and the Drug Guide Medical Review Panel do not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.