Tramadol with acetaminophen

In a combination pill, 75 mg tramadol and 650 mg acetaminophen every 4 to 6 hours as needed.

Constipation; diarrhea; dizziness; drowsiness; lightheadedness; loss of appetite; mental confusion; nausea; shortness of breath; urinary retention; vomiting.

Do not increase the dose on your own or stop treatment abruptly unless told to do so by a doctor. Do not drive, operate machinery or perform other potentially dangerous activities until you know whether the medication will affect your ability to do them safely.

This medicine contains acetaminophen. Do not use with any other products containing acetaminophen. Too much acetaminophen can cause serious liver damage or death. Limit the amount of acetaminophen you take to 3000 mg/day unless otherwise directed by your doctor. Drinking alcohol increases your risk of liver damage. Tell your doctor if you have a history of liver disease or alcohol or drug abuse, or if you have three or more alcoholic drinks daily. Also tell your doctor if you take the blood-thinning drug warfarin (Coumadin). Acetaminophen prolongs the time that drug is active in your body, increasing bleeding risk. Your doctor may need to adjust your dosage. Rarely, acetaminophen may cause serious skin reactions, including Stevens-Johnson syndrome, which can be deadly. Stop taking acetaminophen and call your doctor if you develop a skin rash.

Opioids can slow breathing and suppress the cough reflex. Before taking an opioid, tell your doctor if you have a history of lung disease or breathing difficulties. Taking opioids with certain other drugs can increase the risk of dangerous side effects. Especially tell your doctor if you take antihistamines (allergy medications), tranquilizers, sleeping pills, muscle relaxants or other pain medication, or if you have a history of alcohol or drug abuse.

Seizures have been associated with the use of tramadol. Taking this drug with certain antidepressants or with other opioids may increase this risk.
 

LAST UPDATED: 03/27/2014